Appreciate all the great responses...and the ones that don't really apply either, LOL!
I already have a full size truck, and have had 3 Durango's in the past. Mopar products have been very good to us and I'm inclined to stay with them. The reason for asking about the others was I'm thinking of downsizing as I really only use the truck for towing and occasional trips around town. Just don't need an expensive, newer truck sitting so much...and yes I can afford it. So just thinking about options...
The CVT tranny in the Pathfinder kind of eliminates that one. The Chevy products are out as well due to the bad reviews on towing. The Hyundai & VW would be fine if just occasionally towing, but would get stressed with towing a lot, so they are out. I'm not at all interested in a Highlander or a 4Runner, and I know all about Toyota reliability. I've owned a couple Toyota's, been in a lot more and they just aren't for me. Same with Ford products - no Explorer's or F150 ever! I can't do a BMW either, if I go with a European vehicle it will be the big MB GL/GLS or the Audi Q7.
So what's left?
2014-19 Nissan Armada/Infiniti QX80 (8500 lb towing)
2013-18 MB GL/GLS (7500 lb towing)
2012-19 Audi Q7 (6600/7700 lb towing)
2014-21 Jeep Grand Cherokee (6200/7200/7400 lb towing)
2012-18 Honda Pilot (5000 lb towing)
Adding 2014-20 Lexus GX460 (6500 lb towing)
So I think I'm left with the above to chose from. Maybe another Durango as they were all good to us. And the Jeep GC has a lot of options, easy to get parts and find places to work on them and they do tow boats really well. I do understand that the MB and Audi will be more expensive to repair/maintain. But they also offer a lot of vehicle for the money and I have a pretty good mechanic locally who can work on them. The Pilot, Armada/QX80, and GX460 are all interesting as they would probably do exactly what I need/want at a decent price and with less repair bills as well.
Some really excellent responses and real world experiences - appreciate all of them!