Well, it happened to me. Single axle trailer and a tire blew out on an interstate at 65 mph. Tire was 2 years old with maybe 2000 miles on it. The guy that was behind me pulled over to help and told me he saw it happen and thought I had hit something. No way to tell if that is what happened or not. This tire passed inspection 2 weeks ago.
The trailer was originally equipped with Goodyear Marathons. About 5 years ago I had taken the trailer for the state safety inspection and one of the tires would not pass. I asked the shop if they had them and was told yes. I had already used the spare when the other tire's tread was low so I told them to put two new tires on the trailer and move the better one to the spare position. When I the work was done I looked at the tires and they were Power King Towmaster. My mistake - I should have asked what they were putting on. They didn't carry the Goodyear.
Two years ago I was working on my hubs and noticed that one of them had worn too much and I replaced it with another Power King. That is the tire that had the blowout.
I was able to get to the side of the highway and change the tire. The only damage to the trailer was the wiring for the tail light on that side. It doesn't look like the wheel got damaged; how do I check that?
I have been reading the threads on here about tires and I guess I will put Goodyear Endurance on this time. That leaves the question of the spare. Would you put a new one on there or use the 2006 Marathon or the 2016 Power King? My truck has a towing app that monitors the tire pressure and temperature, so if I ever need to use the spare in regular service it will need to be dismounted and have the TPMS sensor installed. If I am at that point I would just get two new tires if I use one of the older tires for emergency service.