I have 2 main rifles that I use for hunting deer. Weatherby Vanguard 243 and TC Venture 30/06. Both are tack driver's with appropriate Barnes ammo.
The 30/06 shoots 150 grain very accurate but the 185 grain is all over the paper. I have only used Barnes 85 grain in the 243.
Have you found most of your rifles to be picky with ammo?